Equithrive™ is the first equine product line to contain a purified form of the therapeutic compound resveratrol.
Resveratrol is a natural molecule that:
(1) Reduces gene expression of inflammatory enzymes.
(2) Is safe for long-term daily use (“generally regarded as safe” by the FDA).
(3) Does not produce unwanted gastrointestinal side effects.
Equithrive™ Joint is a powdered product that can be administered with a horse’s daily feed ration.
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Dose |
Resveratrol |
Hyaluronic Acid |
Doses per 1-lb Container |
| Loading |
4 scoops |
2 grams |
200 mg |
15 |
| Intensive Support |
4 scoops |
2 grams |
200mg |
15 |
| Maintenance |
2 scoops |
1 grams |
100mg |
30 |
| Ingredients: Resveratrol, Hyaluronic Acid, Grape Skin and Seed Powder, Saccharomyces Cerevisiae 1026, Fermentation Solubles, Diatomaceous Earth. |
Equithrive™ RSV is a veterinary paste that contains 1 gram of resveratrol per 10 cc of product. This product is intended for use in conjunction with Equithrive™ Joint in the days prior to competition or during intense training. Each tube contains 60 cc of paste. Recommended dosage is 10 to 30 cc daily.
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Ingredients: Micronized Resveratrol, Water, Carboxymethylcellulose Sodium, Stevioside, Sodium Benzoate, Natural Apple Flavor, Citric Acid. |
How does resveratrol work?
Other commonly used NSAIDs, such as Bute or Banamine, inhibit both inflammatory cyclooxygenase enzymes (COX-2) as well as the gastro-protective form of the enzyme (COX-1). The COX-1 inhibitory activity of these products and associated gastrointestinal side effects, including ulcers, make them unsafe for long-term daily use.
Conversely, resveratrol does not affect the body’s production of gastroprotective prostaglandins and does not have unwanted gastrointestinal side effects. Rather than inhibiting inflammatory enzymes circulating in the body, resveratrol reduces gene expression of inflammatory mediators, such as COX-2, lipoxygenases, myeloperoxidases, nitrous oxide synthases and tumor necrosis factor alpha (TNFα). The result is that lower concentrations of inflammatory enzymes are circulating in the body.
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